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Problem Tech Solves

Tech Brief

Before Virta, diabetes reversal—where patients achieve A1c (a measure of blood sugar) below 6.5% without the use of diabetes-specific medications—was available only through bariatric surgery or small clinics equipped to provide ongoing nutritional guidance. Bariatric surgery is invasive and expensive, and specialty medical groups don’t have the resources or technology to scale T2D reversal beyond a few local patients. This left the other 30M+ Americans with diabetes without options beyond increasing medications to manage their disease. Enter Virta. Our approach uses decades-old clinical research and cutting-edge telehealth technology to enable previously-unthinkable health outcomes, at scale. For instance, 94% of patients using insulin decrease or eliminate their dosage at one year. 63% of all prescriptions are eliminated at one year. This happens while blood sugar improves by 1.3 points, on par with the most effective T2D drugs. For payers, these types of outcomes represent thousands of dollars in savings for each member or employee with diabetes. Depending on the medication load, payers often see ~$3000-$6000 in savings per patient per year on medication alone. For patients, beyond improving their numbers, we’re seeing incredible anecdotes like “I took my first steps in almost 8 years” & “At the beginning of the program ... because of my back pain issues and MRI report, spine Doctor suggested surgery...well now the pain is gone from 10+ to 0-1.” Two patients even have permanently tattooed the Virta logo on their body, as a testament to their success!

Tech Differentiators

Most digital diabetes programs presume diabetes is chronic and progressive, with a focus on managing symptoms through more medications or increased medication adherence. Virta’s approach is to treat the root cause of diabetes, restoring blood sugar to normal levels while often eliminating the need for medications, including insulin. Virta helps patients achieve these outcomes via its Continuous Remote Care technology. Through an app, Virta patients submit biomarker and symptom data—up to multiple times per day—to enable disease management in real-time. As more pressing issues are surfaced to the top of the list, this AI-enabled technology transforms doctors from working a patient “assembly line” into manning “mission control centers,” effectively managing thousands of patients in near real-time. This allows the treatment to be both cost-effective & efficient. Payers save money on not only medication de-prescription, but also fewer ER visits for T2D complications. Patients, who are members and employees, are generally healthier, happier, & more productive. Beyond that, our patients are the real superheroes. Coming from all walks of life, their stories of success are the company's inspiration. Examples include: - Dulce: After just 7 months, she is off metformin, has lost 35 lbs, & reversed her T2D w/ blood sugar below even the prediabetes threshold. - Chris: Since starting Virta, Chris has lost 110+ pounds, reversed his T2D, and eliminated all diabetes Rxs. But for him, "the most valuable thing I got back was my ability to spend time with my daughter." More stories here: https://www.virtahealth.com/categories/patient-voice


Cost Savings: -- Virta has earned Validation Institute’s most prominent, Level 1 savings validation for delivering unmatched medication cost reductions. Per the analysis, Virta’s validated prescription drug savings amounted to nearly $6k per patient over a two-year period. Clinical Outcomes: -- At the ADA 82nd Scientific Sessions, Virta presented eight new scientific abstracts, covering preliminary 5-year data (duration that is rare in any behavior-based intervention, digital or otherwise) from our controlled, prospective clinical trial, and 2-year real-world outcomes from our partnership with the U.S. Department of Veterans Affairs. Highlights of 5-year data -- Diabetes reversal & remission: One-third of patients completing 5 years achieved sub-diabetic blood sugar and no medications excluding metformin (Virta's definition of reversal) -- 20% of patients completing 5 years achieved diabetes remission (sub-diabetic blood sugar without any diabetes medications for at least 3 months) Medication deprescription: Total diabetes prescriptions were reduced by nearly 50%. Half of those who started on insulin no longer needed it at all. Weight loss: Average weight loss was 7.6%, exceeding the 5% benchmark for clinically-significant weight loss by more than 50% Highlights of Veterans Data -- Note: this is known as a very difficult population to treat, yet our patients experienced excellent outcomes -- Diabetes reversal & remission: One-sixth of patients either reversed their diabetes or achieved full remission at two years. -- Medication deprescription: Total diabetes prescriptions were reduced by one-third. -- Weight loss: Average weight loss was 7%, exceeding the 5% benchmark for clinically significant weight loss by nearly 50%.

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