Developing prescription digital therapeutics and platforms to save lives.

Tech Brief

Oui Therapeutics, Inc. (‘Oui’) was founded in 2018 to specifically address the most important and costly problems in healthcare. Suicide is among the most costly and important problems to address, and there is an extensive amount of research demonstrating effective and efficacious treatments and interventions for its prevention. Thus, Oui’s top priority has been the development of proprietary software to help scale them. In order to accomplish this goal, the Oui team has brought together the nation’s leading experts in suicide prevention ( including Drs. David Rudd and his frequent collaborator Craig Bryan, and Barbara Stanley and Greg Brown) and behavioral health software (including Drs. Seth Feuerstein, Benjamin Bunney, Leng Lee, and Patricia Simon) to solve this problem. Oui’s scientific team includes the inventors of safety planning and lethal means restriction planning as well as psychiatry and psychology faculty members from the University of Memphis, University of Pennsylvania, Columbia University, and Yale University. The Oui team is widely recognized for developing and proving the leading screens, assessments, and treatments for suicidality, including the development of safety planning. The CAPS engineering team is led by experts in design and technology with training from the leading computer science programs in the world, including Stanford, Cornell, and Oxford. Together the Oui team has developed digital, scalable, data driven software specifically for scaling safety planning and lethal means restriction planning. CAPS is designed to reduce and prevent suicide risk. CAPS can be deployed rapidly and made completely anonymous and stigma free.

Problem Tech Solves

There are a limited amount of interventions with demonstrated efficacy for preventing suicide. There are even fewer digital platforms built by the developers of these interventions. Moreover even when clinical workers are trained to deliver interventions for suicide prevention, their fidelity has been shown to dwindle over time. Thus Oui Therapeutics has designed software to augment clinical care delivery and serve as an effective and efficient tool for professionals to use with individuals at risk of suicide. When care workers are paired with the CAPS platform the end result is a unique scalable and effective approach to mitigating the risks of future suicide attempts. The intended audience for our solution is adults at risk for suicide. CAPS can be implemented with health insurance plans and self insured employers that have care workers trained to interact with individuals at risk of suicide. Unlike paper-based or static app-based suicide risk assessments, CAPS suicide risk assessments are customized, dynamic, and can be modified over time.


CAPS Assess and Planning sessions are built on the Safety Planning Intervention (SPI) and Crisis Response Planning (CRP) protocols, which are suicide prevention protocols that have been shown to decrease the risk of suicide attempts. Developers of both protocols (Craig Bryan, Greg Brown, David Rudd, and Barbara Stanley) are collective members of the Oui Team and have signed non-compete agreements to digitize these protocols exclusively with Oui Therapeutics on certain key aspects. Scientifically Validated Protocols: CAPS is built on protocols that are proven to reduce the risk of suicidality in adult populations. This large-scale cohort (n=1,640) comparison study found that SPI was associated with a reduction in suicidal behavior and increased treatment engagement among suicidal patients following ED discharge and may be a valuable clinical tool in health care settings. Stanley B, Brown GK, Brenner LA, et al. (2018). Comparison of the Safety Planning Intervention With Follow-up vs Usual Care of Suicidal Patients Treated in the Emergency Department. JAMA Psychiatry;75(9):894–900 Crisis response planning was more effective than a contract for safety in preventing suicide attempts, resolving suicide ideation, and reducing inpatient hospitalization among high-risk active duty Soldiers (n=97). Bryan CJ, Mintz J, Clemans TA, et al. (2017). Effect of crisis response planning vs. contracts for safety on suicide risk in U.S. Army Soldiers: A randomized clinical trial. J Affect Disord;212:64‐72.